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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MED13L
All Species:
22.12
Human Site:
S1695
Identified Species:
40.56
UniProt:
Q71F56
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q71F56
NP_056150.1
2210
242602
S1695
A
A
E
E
D
S
T
S
G
N
F
W
L
L
S
Chimpanzee
Pan troglodytes
XP_001138050
2188
240763
S1673
T
D
E
S
T
N
S
S
S
V
W
T
L
G
L
Rhesus Macaque
Macaca mulatta
XP_001112106
2210
242628
S1695
A
A
E
E
D
S
T
S
G
N
F
W
L
L
S
Dog
Lupus familis
XP_534693
2280
250152
S1765
T
A
D
E
D
S
T
S
G
N
F
W
L
L
S
Cat
Felis silvestris
Mouse
Mus musculus
Q6JPI3
2207
241740
S1692
T
A
E
E
D
S
S
S
G
N
F
W
L
L
S
Rat
Rattus norvegicus
NP_001101807
1374
149708
R883
D
H
I
P
E
H
M
R
S
S
F
I
L
Q
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509907
2170
238695
S1655
N
K
D
E
S
T
N
S
N
I
W
T
L
G
L
Chicken
Gallus gallus
XP_415317
2195
241321
S1681
T
A
D
E
E
S
A
S
T
N
F
W
L
L
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A2VCZ5
2102
230974
S1602
E
N
C
Q
G
S
S
S
S
V
W
T
I
A
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KTX8
2618
280005
L2109
R
L
A
L
I
A
L
L
R
C
Y
A
E
L
L
Honey Bee
Apis mellifera
XP_393643
1982
216109
I1491
R
A
R
E
R
R
K
I
Q
D
E
M
R
A
L
Nematode Worm
Caenorhab. elegans
Q93442
2862
325119
H2288
P
E
G
H
S
A
L
H
M
R
I
A
I
L
A
Sea Urchin
Strong. purpuratus
XP_001203054
1127
123639
A636
V
S
L
Q
R
N
I
A
F
Q
V
A
N
S
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
53.7
99.2
93.3
N.A.
92.4
57.7
N.A.
53.5
86.4
N.A.
50.2
N.A.
24.8
33.9
21.2
25.6
Protein Similarity:
100
69.3
99.6
94.7
N.A.
95.7
59.9
N.A.
69.7
92.5
N.A.
66.4
N.A.
41.5
50.5
38.5
35.1
P-Site Identity:
100
20
100
86.6
N.A.
86.6
13.3
N.A.
20
66.6
N.A.
13.3
N.A.
6.6
13.3
6.6
0
P-Site Similarity:
100
40
100
93.3
N.A.
93.3
26.6
N.A.
40
80
N.A.
40
N.A.
20
20
26.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
47
8
0
0
16
8
8
0
0
0
24
0
16
8
% A
% Cys:
0
0
8
0
0
0
0
0
0
8
0
0
0
0
0
% C
% Asp:
8
8
24
0
31
0
0
0
0
8
0
0
0
0
0
% D
% Glu:
8
8
31
54
16
0
0
0
0
0
8
0
8
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
8
0
47
0
0
0
0
% F
% Gly:
0
0
8
0
8
0
0
0
31
0
0
0
0
16
0
% G
% His:
0
8
0
8
0
8
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
8
0
8
8
0
8
8
8
16
0
8
% I
% Lys:
0
8
0
0
0
0
8
0
0
0
0
0
0
0
0
% K
% Leu:
0
8
8
8
0
0
16
8
0
0
0
0
62
54
39
% L
% Met:
0
0
0
0
0
0
8
0
8
0
0
8
0
0
0
% M
% Asn:
8
8
0
0
0
16
8
0
8
39
0
0
8
0
0
% N
% Pro:
8
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
16
0
0
0
0
8
8
0
0
0
8
0
% Q
% Arg:
16
0
8
0
16
8
0
8
8
8
0
0
8
0
0
% R
% Ser:
0
8
0
8
16
47
24
62
24
8
0
0
0
8
39
% S
% Thr:
31
0
0
0
8
8
24
0
8
0
0
24
0
0
0
% T
% Val:
8
0
0
0
0
0
0
0
0
16
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
24
39
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _